kuchh companiyaan nae vikretaaon ko jodne aur vaauchar pravisht karne ke kaarya ko bhi alag karti hain. isse kisi karmachaari ke liye asambhav ho jaata hai ki vah khud ko vikreta ke roop mein jode aur fir kisi anya karmachaari ke saath bina saanth-gaanth ke apne naam check kaatein. yeh faail master veindar faail ke roop mein nirdisht hai. yeh company ke aapoortikrtaaon ke baare mein sabhi mahatvapoorn jaankaari ka bhandaar hai. jahaan beejak ke bhugataan ka maamala hai, yeh dendaari lekhon ka sandarbh bindu hai.[5]
san 2000 mein 1.22 log dhoomrapaan karte the. prachalan mein parivartan ka koi anumaan na lagaate hue yeh bhavishyavaani ki gayi hai ki 2010 mein 1.45 billion log aur 2025 mein 1.5 se 1.9 billion log dhoomrapaan kareinge. maan lein ki prasaar ek saal mein 1% kam hota hai aur aay mein 2% ki maamooli vruddhi hoti hai to dhoomrapaan karne vaalon ki sankhya 2010 aur 2025 mein anumaanit 1.3 billion hogi.[13]

gharon mein aam taur par vidyut company, telephone company, kebal teleevijn ya upagrah dish seva, akhbaar ka chanda aur anya aisi niyamit sevaaen dendaari lekhe hain. gruhasth log saamaanyat: check ya kredit card ka upayog karte hue, hastachaalit tareeke se maasik aadhaar par inka dhyaan rakhate aur bhugataan karte hain. vyaapaar mein, aam taur par A/P faail mein vyaapak sevaaen shaamil hoti hain aur saamaanya roop se lekhaakaar ya bahi-khaata likhnevaale, jab unhein beejak milta hai to is dendaari khaate mein aane vaale dhan aur jab ve bhugataan karte hain, to is khaate se jaane vaale dhan ke pravaah ki khoj-khabar ke liye lekhaankan software ka prayog karte hain. badi companiyaan ek sangathan ke beejakon ke sansaadhan mein prayukt kaagj aur hastachaalit tatvon ko svachaalit karne ke liye teji se vishesh dendaari lekhon ke svachaalan ka prayog kar rahi hain.
jab tambaakoo ka sevan kiya jaata hai, jyaadaatar nikoteen jhulas jaata hai. haalaanki, ek khuraak halki shaareerik nirbharata ke liye paryaapt hai aur ek majaboot manovaigyaanik nirbharata ko halka karne ke liye paryaapt rahati hai. vahaan tambaakoo ke dhuen mein maujood acetaldehyde se haaramon(ek MAO avarodhak) ka gathan bhi hota hai. aisa lagta hai ki nikoteen ke nashe mein ek mahatvapoorn bhoomika nibha raha hai- nikoteen ki uttejanaaon ke javaab ke roop mein ek javaabi kaarravaai ke taur par naabhik accumbens mein ek dopamine ki suvidha jaari ki gayi.[51] adhyayan ke liye choohe ka upayog karke yeh doharaaya gaya ki nikoteen ke upayog ke baad kam jimmedaar naabhik accumbens koshikaaen sudrudheekaran ke liye jimmedaar hain, jo aparaadh mein fansaane ki kai ghatnaaon, jismein keval nikoteen hi naheen isi tarah ki cheejein majabooti ko kam kar deti hain.[52]
1980 ke dashak mein mile vaigyaanik pramaan ke anusaar tambaakoo companiyaan ne daava kiya hai ki laaparavaahi baratne ka kaaran svaasthya par padne vaale pratikool prabhaav se pehle unka anajaan hona tha ya paryaapt vishvasaneeyata ka abhaav tha. svaasthya adhikaariyon ne 1998 tak in daavon ka saath diya jiske baad unhonne apni sthiti ulat di. tambaakoo pradhaan niptaan samjhauta (the tobaiko master saitalameint egreemeint) mool roop se chaar sabse badi tambaakoo companiyon aur 46 raajyon ke ameriki etorni general ke beech hua. tambaakoo ke kuchh khaas prakaar ke vijnyaaapanon par pratibandh laga diya gaya aur svaasthya muaavaje ke taur par bhugataan ko aavashyak kar diya gaya, jo baad mein sanyukt raajya America ke itihaas mein sabse bade naagrik niptaan ke roop saamane aaya.[36] 

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