Germany mein dhoomrapaan virodhi samooh aksar sharaab virodhi samoohon ke saath jud gaye,[30] tambaakoo ke sevan ke khilaaf der taibakajejaner Der Tabakgegner (tambaakoo pratidvandvi) patrika mein 1912 aur 1932 mein prakaashit lekh mein pehli baar vakaalat ki gayi. san 1929 mein Germany ke dresaden ke fritj likint ne ek lekh prakaashit kiya jismein fefadon ke Cancer-tobaiko link ka aupachaarik saankhyikeeya saboot tha. edaulf hitlar ne ghanaghor avasaad ke dauraan dhoomrapaan karne ki lat ko paise ki barabaadi kehkar ninda ki thi aur baad mein usane drudh vaktavya diye.[31] yeh aandolan aage chalakar naaji prajanan neeti ke kaaran aur majboot hua jismein mahilaaon ke dhoomrapaan ko ek jarman parivaar mein patniyon aur maataaon ke liye anupayukt maana gaya.[32]

iske vipreet, kuchh gair-vaigyaanik adhyayan hain jismein se ekcheck ganaraajya ke Phillip mauris[72] dvaara aur doosra kaato Institute dvaara kiye gaye hain,[73] jo vipreet sthiti ka samarthan karte hain. adhyayan ki na to saathiyon dvaara sameeksha ki gayi aur na hi kisi vaigyaanik patrika mein prakaashit kiya gaya aur kaato Institute ko ateet mein tambaakoo companiyon se dhan praapt hua tha.[krupaya uddharan jodein] Phillip mauris ne spasht roop se apne poorv ke adhyayan ke liye yeh kehkar maafi maangi hai ki: "is adhyayan ke liye dhan aur saarvajanik vigyapti mein anya baaton ke alaava dhoomrapaan karne vaalon ki samay se pehle hone waali mauton se check ganaraajya ki vistrut kathit laagat bachat ki baat ek ek bhayaanak nishkarsh hai, saath hi saath vah poorn roop se buniyaadi maanaveeya moolyon ki upeksha hai, jo asveekaarya hai. hamaari tambaakoo companiyon mein se ek ne is adhyayan ka kaaryabhaar diya tha, jo ek bhayaanak galati naheen thi, balki vah anuchit tha. Phillip mauris mein ham sabhi, yeh koi maayane naheen rakhata ki ham kahaan kaam karte hain, is kaarya ke liye kshamaapraarthi hain. vaastav mein dhoomrapaan se koi faayda naheen, uske kaaran gambhir aur mahatvapoorn rog hote hain."[72]
pitsabarg mein seint kleyar aspataal ke ek RFID aur baarakod aadhaarit bedasaaid dava satyaapan pranaali laagoo ki hai jo dava trutiyon ko kam kar ke rogi suraksha mein sudhaar karti hai. IV pampon ke maadhyam se di gayi davaaon sahit koi bhi dava dene se pehle, narsein rogi ke ID aur davaaon ki jaanch ke liye ek portebal RFID reedar aur baarakod skainar se yukt ek PDA ka prayog karti hain.[60]
upakaran pravaah ka lekhan aur deebaging, digital design ka utpaadan karne waali companiyon mein ek sthaapit engineering visheshata hai. upakaran pravaah aam taur par ek vistrut computer faail ya faailon ke set mein mit jaata hai jo yeh varnan karta hai ki kaise laujik ka bhautik roop se nirmaan karein. ismein aksar ek ekeekrut paripth ya mudrit sarkit board par traanjistar aur taar kheenchne ke nirdesh shaamil hote hain.
1980 ke dashak mein kuchh shodhakartaaon ne paaya ki lagbhag sabhi tulyakaalik rajistar-transfer masheenon ko first-in-first-out tulyakaalan laujik ka upayog karke atulyakaalik dijaainon mein parivrtit kiya ja sakta tha. is yojana mein digital machine, ek data pravaah ke ek set ke roop mein pahachaani jaati hai. pravaah ke har kadam mein, ek atulyakaalik "tulyakaalan sarkit" nirdhaarit karta hai jab us step ka aautaput thos aur ek prastut sanket deta hai ki un stejon ko "deta ko pakado" jismein un stejon ke input mein prayog hua hai. iske liye kuchh apekshaakrut saral tulyakaalan sarkit ki aavashyakta hai.
lekin, yatha 2008, yeh takaneek kai chhote pustakaalayon ke liye bahut mahangi hai aur ausat aakaar ke pustakaalaya ke liye roopaantaran avadhi 11 maheene anumaanit hai. 2004 ka ek dach anumaan tha ki ek pustakaalaya jo prati varsh 100,000 kitaabein padaan karta hai use €a50,000 ki laagat par yojana banaani chaahiye (pradaan aur vaapasi station: pratyek 12,500, ditekshan porches pratyek 10,000; taig pratyek 0.36). RFID dvaara karmachaariyon par se ek bada bojh kam kar dene ka matlab hai ki kam karmachaariyon ki jaroorat, jiske parinaamasvaroop unamein se kuchh ko nikaal diya jaaega,[29] lekin aisa abhi tak uttar America mein naheen hua hai jahaan haal ke sarvekshanon ne ek bhi pustakaalaya naheen paaya jahaan RFID ke kaaran karmachaari ko hataaya gaya ho. balki, karmiyon ke liye pustakaalaya bajat kam kiya ja raha hai aur buniyaadi suvidhaaon ke liye badhaaya ja raha hai, jisse pustakaalayon ke liye yeh aavashyak ho gaya hai ki ve karmachaariyon ki kami ko poora karne ke liye svachaalan ko badhaaen. iske alaava, RFID dvaara kiye jaane vaale kaarya mote taur par laaibreriyn ke praathamik kaarya naheen hain. Netherland mein ek khoj yeh hai ki, lenevaale is tathya se khush hain ki ab savaalon ke javaab dene ke liye aur adhik karmachaari upalabdh hain.
1995 se 1970 ke beech gareeb vikaasasheel deshon mein prati vyakti cigarette ki khapat mein 67 pratishat ki vruddhi hui hai, jabki usamein ameer viksit duniya mein 10 pratishat giraavat aayi hai. dhoomrapaan karne vaalon mein se assi pratishat ab kam viksit deshon mein rahate hain. 2030 tak vishv svaasthya sangathan (WHO) ki bhavishyavaani hai ki 10 million logon ki maut prativrsh dhoomrapaan se sambandhit beemaariyon se hogi jo duniya bhar mein maut ka ek sabse bada kaaran hoga, mahilaaon mein iski sabse badi vruddhi hogi. WHO ki bhavishyavaani hai ki 20 veen sadi mein dhoomrapaan se hui mauton ki daron mein 21 veen sadi mein das guna vruddhi hogi. ("Washington"(Washingtonian) patrika, December 2007).
sansthaan ki ye sahaayak khaata bahiyaaain hai. deya khaata bahi mein sansthaan ke sabhi deya khaate tatha praapya khaata bahi mein uske sabhi praapya khaate ankit rahate hain. yadi khaaton ki sankhya adhik hui to ek se adhik khaata bahiyaaain varnaanukram ya bhaugolik aadhaar par suvidhaanusaar bhi ye bahiyaaain rakhi jaati hai. sansthaan ke samaanya khaate mein bhi deya tatha praapya dhan ka aalekh rahata hai. in khaata bahiyon ki alag vyavastha shramavibhaajan ke sahaj laabh ke kaaran ki jaati hai kyonki iske dvaara vitt vibhaag ko baaaint kar tatha alag svatantr roop se bhi kaam karne mein sahaayata milti hai. saath hi shram aur samay ki bachat hoti hai. hisaab kitaab ke Milan mein bhi isse sahaayata milti hai kyonki sansthaan ke saamaanya khaate se in bahiyon ke khaate ka santulan samay samay par hota rahata hai jisse bhool chook ki chhaanabeen bhi aasaani se ho jaati hai. bade vyaapaarik sansthaanon mein in sahaayak bahiyon ka upayog vyaapak paimaane par kiya jaata hai.
After the Iranian Revolution, Pakravan was among the first of the Shah's officials to be executed. He was not allowed to have access to a lawyer and the charges filed against him were vague. Given the fact that he was retired at the time of the revolution, his execution seemed all the more unjust. Pakravan was a key player in convincing the Shah to commute the death sentence on Khomeini in 1963 and instead sending him to exile. Khomeini was first sent to Turkey, and then to Iraq, where he stayed until his expulsion and relocation to France in 1978.
hamane pahale se hee sanvardhit vaastavikata (eaar) aur aabhaasee vaastavikata (veeaar) praudyogikee ke lie 2016 mein kuchh pramukh kadamon ko dekha hai. okulas ripht ko sakaaraatmak risepshan ke lie jaaree kiya gaya tha, aur hajaaron veeaar aips aur gems ka paalan kiya gaya tha. hamane piksamon go bhee dekha, eaar gem, 100 miliyan se adhik daunalod ke saath visphot kiya. baajaar eaar aur veeaar ke lie taiyaar hai, aur in epleekeshans ke lie hamaare paas pahale se shuruaatee stareey upakaran aur tek mil chuke hain, lekin isase pahale ki ham cheejen sachamuch le jaenge, agale saal hone ja rahe hain. ek baar ve karate hain, aapako vyaavahaarik roop se har cheej ke eaar aur veeaar sanskaranon ke lie taiyaar rahana hoga- aur paalan karane ke lie paryaapt vipanan avasaron ka paalan karana hoga.
kai deshon jaise Ireland, laataviya, estoniya, Netherland, France, Finland, naarve, Canada, Australia, sveedan, Portugal, Singapore, Italy, Indonesia, Bhaarat, lithuaaniya, chili, Spain, aaisalaind, United Kingdom, sloveniya aur maalta ne saarvajanik sthaanon par dhoomrapaan ke khilaaf kaanoon banaaye hain, jinmein baar aur restaurant bhi shaamil hain. restaurant mein bhi kuchh nyaayaalayon ne anumati di hai ki ve sunishchit dhoomrapaan kshetron (ya dhoomrapaan nishedh ke liye) ka nirmaan karein. sanyukt raajya America mein kai raajyon mein restaurant mein dhoomrapaan nishedh hai aur kuchh sharaabakhaanon mein bhi dhoomrapaan nishedh hai. Canada ke praanton mein inador kaaryasthalon aur saarvajanik sthaanon par dhoomrapaan avaidh hai jinmein sharaabakhaane aur restaurant bhi shaamil hain. 31 March 2008 ko Canada ne sabhi saarvajanik sthaanon par dhoomrapaan par pratibandh lagaaya, saath hi saath kisi bhi saarvajanik jagah ke pravesh dwaar ke 10 meter ke bheetar bhi yeh pratibandh laagoo hai. Australia mein dhoomrapaan par pratibandh har raajya mein alag-alag hai. vartamaan mein kveensalaind mein sabhi saarvajanik sthalon ke androoni hisson mein dhoomrapaan par poornataya pratibandh hai (jinmein kaaryasthal, sharaabakhaane, pab aur bhojanaalaya shaamil hain) saath hi saath aavaajaahi vaale samudra tat aur kuchh saarvajanik sthalon ke baahari kshetr shaamil hain. tathaapi, chihnit dhoomrapaan kshetr apavaad hain. Victoria mein train stationon, bas staap aur train staap par dhoomrapaan nishiddh hai aur in saarvajanik sthaanon par jahaan dhoomrapaan se parivhan ka intajaar kar raha gair dhoomrapaan karne wala prabhaavit ho sakta hai aur 1 July 2007 se use sabhi inador saarvajanik sthalon par laagoo kar diya gaya hai. New Zealand aur Brazil mein saarvajanik sthaanon se sanlagn kshetr mein dhoomrapaan karne par pratibandh laga diya hai, jismein mukhya roop se sharaabakhaana, restaurant aur pab shaamil hai. Hongkong mein 1 January 2007 ko kaaryasthal mein dhoomrapaan par pratibandh laga diya gaya jaise restaurant, karaaoke rooms, imaaraton aur saarvajanik park. sharaab parosane vaale baar jinmein 18 varsh ki aayu se kam ke logon ko pravesh naheen dete, ko 2009 tak chhoot di gayi. romaaniya mein railgaadiyon, metro stationon, saarvajanik sansthaanon (jahaan aamtaur par nirdisht sthal baahar hai) aur saarvajanik parivhan mein dhoomrapaan avaidh hai.
Vyapar is the simplest to use Accounting, Invoicing & Inventory management software that can be used by any kind of businessman. It lets you track your Daily Transactions, Cash-in, Cash-out, Create personalized GST compatible Invoices, Manage Cheque's and Bank Accounts, Manage your Inventory with Low stock reminders, View how your business us doing with various Reports, send personalized Bulk messages to all your parties, supports Thermal Printer, has a Barcode Scanner, It is supports Multiple Company / Firms and so much more.. In this Digital India era, use Vyapar to make your Business more Smart and be Digital. It is available in both Desktop/ PC version and Mobile !
अमेरिका की प्रबंधन पत्रिका हार्वर्ड बिजनस रिव्यू में कल प्रकाशित एक लेख में कहा गया है कि भारत में सरकार की अगुवाई में डिजिटल उठा-पटक की एक अनोखी कहानी कही जा रही है और वहां डिजिटल रूप से सशक्त समाज का निर्माण किया जा रहा है।‘कैसे भारत पहली डिजिटल अर्थव्यवस्था की ओर बढ़ रहा है’ शीर्षक से लिखे लेख में कहा गया है, “भारत ने इसकी चुनौतियों को कम करने के लिए डिजिटल प्रक्रिया को धीमा करने के बजाए विपरीत दृष्टिकोण अपनाया है और डिजिटल प्रक्रिया को तेज कर दिया है ताकि देश आर्थिक एवं सामाजिक क्षेत्र में समावेशी विकास हासिल करने की पूरी संभावनाओं का लाभ उठा सके।
1612 mein jemsataaun ke avasthaapan ke chhah saal baad John raalf pehle adhivaasi hain jinhonne tambaakoo ki ek nakadi fasal ke roop mein safalataapoorvak kheti ki. tambaakoo ki maang mein teji se vruddhi hui, use "bhoora sona" kaha gaya, kyonki usane sone ke abhiyaan mein vifal varjeeniya ko share company mein punarjeevit kar diya.[21] puraani duniya ki maangon ko poora karne ke liye tambaakoo ki paidaavaar lagaataar ki gayi jiske parinaamasvaroop jameen ki urvara shakti sheegra hi kam ho gayi. isne pashchim ko ek agyaat mahaadveep mein basane ke liye prerak ka kaarya kiya aur isi tarah tambaakoo utpaadan ka ek vistaar hua.[22] bekan vidroh ke pehle tak anubandhit daasata hi praathamik shram bal ka aadhaar thi jiske kaaran das pratha par dhyaan kendrit hua.[23] yeh pravrutti ameriki kraanti ke baad kam hui aur daasapratha laabhaheen maani gayi. haalaanki yeh pratha 1794 mein punarjeevit ho gayi jab kapaas ki charkhi ka aavishkaar hua.[24][page needed]
tambaakoo ek krushi utpaad hai jo nikoteeniya prajaati ke paudhon ki taaja pattiyon ka prasanskaran hai. is prajaati mein kai upajaatiyaan hain, haalaanki nikoteeniya tabaakum (Nicotiana tabacum) saamaanyat: ugaaya jaata hai. nikoteeaana rastika (Nicotiana rustica) nikoteen ki uchch saandrata ke maamale mein doosare number par hai. in pattiyon ki kheti hoti hai aur dheeme okseekaran ki suvidha aur tambaakoo ke patte mein kairoteenauyad ko kam hone diya jaata hai taaki vah svasth ho jaaye. isse tambaakoo ke patton mein kuchh yaugik taiyaar hote hain jo meethi ghaas, chai, tel gulaab ya fal jaisa khushaboodaar jaayaka paida karte hain. paikejing se pehle tambaakoo aksar nashe ki shakti badhaane ke liye anya yogaj ke saath sanyukt roop se rakha jaata hai taaki utpaad ka peeech (pH) badal jaaye ya dhoomrapaan ka prabhaav ya svaad behtar ho jaaye. sanyukt raajya America mein in yojakon mein 599 padaarthon ka niyman kiya gaya hai.[8] is utpaad ko uske baad prasanskrut aur paik kar upabhokta baajaar ke liye bhej diya jaata hai. khapat ke saadhan ke taur par sakriya tatvon ke saath kam gaun-utpaad ko naye tareeke ke roop mein sammilit kar is kshetr mein vyaapak sambhaavnaaon ka vistaar kiya gaya hai.
saan Diego, California, metropolitan traanjit system (MTS), north County traanjit distrikt (NCTD) aur the sain Diego asosiyeshan of gavarmeint (SANDAG) ek ri-raaitebal RFID smart card ka upayog karti hai jise sthaaneeya taur par kampaas card ke roop mein nirdisht kiya jaata hai aur bason aur railgaadiyon ki yaatra aasaan banaane ke liye dainik, saaptaahik ya maasik paas ya nakad moolya ke roop mein upayog kiya ja sakta hai. 

kreteks ek cigarette hai jo tambaakoo, laung aur ek svaadisht chatani ke ek jatil mishran ke masaale se bani hai. yeh pehli baar kudus, jaava mein 1880 ke dashak mein pesh ki gayi, jo fefadon ko laung ke aushadheeya yugenol (eugenol) dene ke liye banaayi gayi thi. tambaakoo ki gunavatta aur vividhta ne kretek ke utpaadan mein mahatvapoorn bhoomika ada ki kyonki kretek mein 30 se adhik prakaar ke tambaakoo sammilit ho sakte hain. laung ki kaliyon ke kiye gaye chhote-chhote tukado mein tambaakoo ka 1/3 vajan ka mishran uske svaad ko badhaata hai. sanyukt raajya America ke kai raajyon mein kreteks par pratibandh hai[krupaya uddharan jodein] aur sanyukt raajya America mein 2004 mein tambaakoo aur menthaul ke alaava anya masaalon ka "vishesh svaad" hone ke kaaran kreteks ko cigarette mein vargeekrut na kar use nishiddh kar diya gaya.[44]
iski tulana mein atulyakaalik system ka design bahut kathin hota hai kyonki sabhi sambhav samay mein bhi sambhaavit state ka vichaar kiya jaana chaahiye. nyoonatam aur adhiktam samay ke table ke nirmaan ke sabse saamaanya vidhi ke anusaar ismein saare state vidyamaan ho aur vaise state ke mineemaaij ke liye sarkit ko samaayojit kiya jaata hai aur jo iske sabhi hisson ke susangat state mein samay-samay par jaane ke liye sarkit ko baadhya kare. (ise "self-reesinkronaaijeshan" kaha jaata hai.) aise saavdhaan design ke bina sanyogavash atulyakaalik laujik ka utpaadan karna aasaan hai jo "asthir" hai aur vaastavik electronics hai jismein apratyaashit parinaam hote hain kyonki electronic upakaranon ke moolyon mein chhote badlaavon ki vajah se sanchit vilamb hota hai. kuchh sarkit (jaise sinkronaaijr-flip flop, svich debaaunsar aur jo baahari anasinkronaaijd ko atulyakaalik laujik sarkit mein pravesh karne ki anumati deta hai) sahaj roop se apne design mein antarnihit atulyakaalik rahe hain aur is tarah hi vishleshan kiya jaana chaahiye.
tambaakoo dhoomrapaan ek aisa abhyaas hai jismein tambaakoo ko jalaaya jaata hai aur usaka dhuaan ya to chakha jaata hai ya fir use saans mein kheencha jaata hai. iska chalan 5000-3000 E.poo.ke praarambhik kaal mein shuroo hua.[1] kai sabhyataaon mein dhaarmik anushthaanon ke dauraan ise sugandh ke taur par jalaaya gaya, jise baad mein aanand praapt karne ke liye ya fir ek saamaajik upakaran ke roop mein apnaaya gaya.[2] puraani duniya mein tambaakoo 1500 ke dashak ke antim daur mein prachalit hua jahaan isne saajha vyaapaarik maarg ka anusaran kiya. haalaanki yeh padaarth aksar aalochna ka shikaar banta raha hai, lekin iske baavajood vah lokapriya ho gaya.[3] jarman vaigyaaniko ne aupachaarik roop se der se 1920 ke dashak ke ant mein dhoomrapaan aur fefade ke Cancer ke beech ke sambandhon ki pehchaan ki jisse aadhunik itihaas mein pehle dhoomrapaan virodhi abhiyaan ki shuruaat hui. aandolan tathaapi dviteeya vishv yuddh ke dauraan dushmanon ki seema mein pahunchane mein naakaam raha aur uske baad jald hi alokapriya ho gaya.[4] 1950 mein svaasthya adhikaariyon ne fir se dhoomrapaan aur Cancer ke beech ke sambandh par charcha shuroo ki.[5] vaigyaanik pramaan 1980 ke dashak mein praapt hue, jisne is abhyaas ke khilaaf raajaneetik kaarravaai par jor diya. 1965 se viksit deshon mein khapat ya to ksheen hui ya fir usamein giraavat aayi.[6] haalaanki, vikaasasheel duniya mein badhat jaari hai.[7]
↑ Kulikoff, Allan (1986-08-01), Tobacco and Slaves: The Development of Southern Cultures in the Chesapeake, The University of North Carolina Press, aai॰aऍsa॰abee॰aऍna॰ 978-0807842249, http://books.google.com/books?id=NCvU9_bj-1QC&printsec=frontcover&dq=Tobacco+%26+Slaves:+The+Development+of+Southern+Cultures+in+the+Chesapeake, abhigman tithi: 2009-03-22
pipe dhoomrapaan mein aamtaur par tambaakoo ke dahan ke liye ek chhota sa kaksh (katora) aur ek patali nalika (danda) shaamil hai, jo mukhapatr (thoda) mein samaapt hota hai. tambaakoo ke kase tukadon ko kaksh mein rakha aur prajvalit kar diya jaata hai. pipe mein dhoomrapaan ke liye tambaakoo aksar bahut dhyaan dekar istemaal kiya jaata hai aur svaad ki baareekiyon ki mishrit upalabdhata anya tambaakoo utpaadon mein upalabdh naheen hai.
FDA ke anusaar, RFID chip ka pratyaaropan se chikitsa sambandhit sambhaavit khatre bhi hain. bijli ke khatre, MRI asangati, pratikool ootak pratikriya aur pratyaaropit traansapondar ka pravaas, kuchh sambhaavit khatre hain jo vereechip ID pratyaaropan upakaran se jude hain, khaadya evam aushadhi prashaasan (FDA) dvaara jaari ek 12 October 2004 ke patra ke anusaar.[47]
sanbhaar-tantr aur parivhan, RFID praudyogiki ke kaaryaanvayan ke pramukh kshetr hain. udaaharan ke liye, yaard prabandhan, shiping aur maal dhulaai aur vitran kendra, kuchh aisi jagahein hain RFID traiking praudyogiki ka istemaal kiya jaata hai. duniya bhar ki parivhan companiyaan, vyaapaar moolya aur kaaryakushalata par RFID praudyogiki ke prabhaav ke kaaran isko tavajjo deti hain.
choonki ve ek aisi gatividhi mein lipt hote hain jiska svaasthya par nakaaraatmak prabhaav padta hai, at: aise log jo log dhoomrapaan karte hain, ve apne vyavahaar ko yuktisangat banaane ke liye prayatnashali rahate hain. doosare shabdon mein ve sveekaaryata viksit karte hain, jaroori naheen ki unke paas yeh taarkik kaaran ho ki unke liye dhoomrapaan ki sveekaaryata kyon hai. udaaharan ke liye, ek dhoomrapaan karne wala apne vyavahaar ka auchitya yeh kehkar saabit kar sakta hai ki har koi marata hai aur isliye vaastav mein cigarette kuchh bhi naheen badalti. ya ek vyakti auchitya saabit karne ke liye yeh vishvaas jata sakta hai ki dhoomrapaan tanaav se raahat ya anya laabh dilaata hai. is prakaar ki maanyataaenchinta se rokati hain aur log dhoomrapaan jaari rakhate hain.[krupaya uddharan jodein]

enbeded software design imyooniti aveyar prograaming ka prayog karta hai, jaise avarodh nirdesh ke saath aprayukt kaaryakram smruti ke roop mein bharne ka prayaas karta hai jo truti ke pun: praapti kaaryakram ki or sanket deta hai. is vifalta ke khilaaf raksha mein madad karta hai jo micro kantrolar anudesh soochak ko bigaad sakte hain, jo anyatha yaadruchhik code ke nishpaadit ka kaaran ban sakte hain.
jab tambaakoo ka sevan kiya jaata hai, jyaadaatar nikoteen jhulas jaata hai. haalaanki, ek khuraak halki shaareerik nirbharata ke liye paryaapt hai aur ek majaboot manovaigyaanik nirbharata ko halka karne ke liye paryaapt rahati hai. vahaan tambaakoo ke dhuen mein maujood acetaldehyde se haaramon(ek MAO avarodhak) ka gathan bhi hota hai. aisa lagta hai ki nikoteen ke nashe mein ek mahatvapoorn bhoomika nibha raha hai- nikoteen ki uttejanaaon ke javaab ke roop mein ek javaabi kaarravaai ke taur par naabhik accumbens mein ek dopamine ki suvidha jaari ki gayi.[51] adhyayan ke liye choohe ka upayog karke yeh doharaaya gaya ki nikoteen ke upayog ke baad kam jimmedaar naabhik accumbens koshikaaen sudrudheekaran ke liye jimmedaar hain, jo aparaadh mein fansaane ki kai ghatnaaon, jismein keval nikoteen hi naheen isi tarah ki cheejein majabooti ko kam kar deti hain.[52]

kuchh dhoomrapaan karne vaalon ka tark hai ki dhoomrapaan ke avasaadak ka prabhaav unki nason ko shaant karta hai, aksar ekaagrata badhaane mein madad karta hai. haalaanki inpeeriyl college London ke anusaar, "nikoteen uttejak aur avasaad donon ka prabhaav dene lagta hai aur yeh sambhaavana hai ki yeh prabhaav kisi bhi samay upayogakarta ki manosthiti, paryaavaran aur upayog ki paristhitiyon dvaara nirdhaarit hota hai. adhyayan mein yeh bhi sujhaav diya gaya hai ki kam khuraak ka ek avasaadak prabhaav hai, jabki jyaada khuraak lene ka uttejak prabhaav hota hai.[67] tathaapi nikoteen ke upayog ke prabhaav aur nikoteen chhodne ke prabhaav ko alag karna asambhav hai.[krupaya uddharan jodein]
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